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The screening cascade employs cellular phenotypic assays based on mitotic index and nuclear p53 protein accumulation.
cNottingham grade based on mitotic index, histologic grade, and nuclear grade.
dComposite score based on mitotic index, histologic grade and nuclear grade.
The tumour is of intermediate or high grade, based on mitotic index or Ki-67.
A prognostically relevant discrepancy was observed in 7.2% of cases (when the mitotic index scores would have resulted in different multivariate prognostic index estimates, based on mitotic index, tumour size and lymph node status).
Results have highlighted a strong correlation between cytoplasmic (altered) CD117 immunoexpression and increased cell proliferation and higher histological grade (itself partly based on mitotic index) when compared with the normal, membrane-associated expression pattern.
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They are further divided into well-,moderately, or poorly differentiated tumors based on mitotic and Ki-67 indices.
We also analyzed the effect of 5-AC and TSA on mitotic index.
Estimates of the duration of metaphase in the two kinds of tumour are also offered, based on the natural mitotic index in six neuroblastomas and five nephroblastomas.
GISTs can be classified as benign, borderline, or malignant tumours based on tumour size, mitotic index, and the invasion of surrounding tissues, and the majority of these tumours are clinically rather non-aggressive [ 3].
None of these studies examined the effects of elevated PCO2 on mitotic indices of zooxanthellae or expulsion rates.
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