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In the μTAS research field, which is a part of biochemical engineering, the technologies of organ-on-a-chip, based on microfluidic devices built using microfabrication, have been widely studied recently as a novel in vitro organ model.
Recent technological advances in cancer research, based on microfluidic devices, will be addressed to illustrate the potential of these new microsystems as powerful diagnostic tools, particularly when multiple technologies are combined to complement each other in engineering the next generation of miniaturised medical diagnostic devices.
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While traditionally, LOC devices are primarily based on microfluidic systems, in this review article, we make a case for utilizing millifluidic systems for more efficient synthesis, bio-functionalization and in vitro studies of inorganic nanomaterials tailor-made for biomedical applications.
We describe a high throughput gene expression platform based on microfluidic dynamic arrays.
Alternative routes are in the further development of devices based on microfluidics, which may also be combined with dielectric elastomer actuators.
This paper describes a method for the production of lipid microparticles (SLM) based on microfluidics using a newly designed modular device constituted of three main parts: a temperature control, a co-flow dripping element and a congealing element.
An alternative means based on microfluidics biomarker detection is then presented.
Analyses based on microfluidics are fast and require only a small amount of sample material.
Although there are a large number of methods for generating and experimenting with droplets on microfluidic devices, the dispensing of droplets from these microfluidic devices is a challenge due to aggregation and merging of droplets at the interface of microfluidic devices.
Indeed, rectilinear and radial channels for parallel high-throughput analysis have been designed on microfluidic devices in DNA assays.
Results from the present study may turn out to be useful in designing lab on a chip based microfluidic devices transporting bio-fluids such as blood, saliva and mucus by means of electroosmotic mechanisms.
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