Although a few studies on microarray analysis of individual preimplantation embryos of cattle have been reported [30], [31], the results are not entirely satisfactory because they are based on microarray analyses using a small number of probe sets or because only a limited number of analyses were performed.
In course of probe design for DNA microarray development, each of the markers yielded a high number of potentially species-specific probes in silico, although many of them were rejected based on microarray hybridisation experiments.
The ins-13 probe is not specific, and it appears to report expression of acdh-2 based on microarray analysis [17].
The identification of the IgSF repertoire expressed by blood cells was based on matching microarray probes to 2 existing reference sets: (1) our manually curated human IgSF reference set defined previously; and (2) the subset of Homo sapiens Ensembl v46, gene predictions that received significant hits by either PFAM or SUPERFAMILY, hidden Markov models that represent IgSF domain sequences.
A major goal for diagnostic research is to develop diagnostic procedures based on inexpensive microarrays that have enough probes to detect certain diseases.
Our method to analyze 3'UTR regulation was based on comparison of microarray probes targeting cUTRs with those targeting aUTRs with respect to intensity changes between samples in a sample set (Figures 1 and S1).
Then the significant enrichment GO terms for each cluster were examined using hypergeometric test with P-value ≤ 0.01 based on the whole microarray probe sets GO analysis results.
Analysis of the continuous expression profiles comprising of 51 microarray data, was based on 29,119 probes with raw signal intensities above 100 in at least one sample.
Following recent recommendations [14], genotype results of the ACTN3 R577X polymorphism were replicated in a different laboratory (Progenika Biopharma, Parque Tecnológico de Zamudio, Derio-Vizcaya, Spain) using a different technology, i.e. newly developed low-density DNA microarray based on allele-specific probes.
According to the alignments, Salmonella and non-pathogenic E. coli strains could be clearly typed based on the probes included on the microarray although their genome sequences did not cover the full set of capture probes designed for these groups.
