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We successfully predicted imprinting in additional strains based on methylation variability.
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(A) PCA analysis based on methylation profile of 26 CpG loci from muscle tissue.
PCA of human tissues and cells based on methylation haplotype loads in MHBs regions.
(D) Average methylation levels based on methylation of individual CpGs in the promoter and first exon of rod and phototranduction genes were reduced during retinal development.
Two additional filters are based on methylation rates.
A smoking score based on methylation profile was constructed.
A sensitive electrochemical method for detection of DNA methylation and assay of DNA methyltransferase (Dam) was investigated based on methylation-sensitive restriction endonuclease, DNA-Au bar bar code and enzymatic signal amplification.
We generalized the recent finding on methylation variability in cancer research to obesity and demonstrated that differential variability is also an important feature of obesity-related methylation changes.
In conclusion, we generalized the recent finding on methylation variability in cancer research to obesity and demonstrated that differential variability is also an important feature of obesity related methylation changes.
Thus, if a gene involved in growth and development is less active in adulthood, meQTLs could be less detectable in adults based on the variability in DNA methylation levels of that gene.
We further investigated the extent to which low-level arsenic exposure in utero was associated with genome-wide DNA methylation variability, assessed using PCA based on DNA methylation in cord blood.
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