Sentence examples for based on mesenchymal stem from inspiring English sources

Therapies based on mesenchymal stem cells (MSC) have been shown to have potential benefit in several clinical studies.

Because of a limited supply of allogeneic bone, tissue engineering and regeneration of the bone based on mesenchymal stem cells has raised a major research interest.

One US Patent of H. Ralph Snodgrass describes a method for toxicity evaluation based on mesenchymal stem cells (MSCs); in his study mammalian MSCs were used and molecular profiles were correlated with the chemical compositions' noxiousness [9].

Since affected tissues in age-associated disorders and in pathological aging are mainly of mesenchymal origin we propose a model of human aging based on mesenchymal stem cells (hMSCs) which accumulate prelamin A. We demonstrate that prelamin A-accumulating hMSCs have a premature aging phenotype which affects their functional competence in vivo.

Cell therapy studies based on mesenchymal stem cell (MSC) transplantation noted the potential benefit of neural induction by neurogenin 1 from transplanted MSCs in the delay of disease onset and in the enhancement of motor functions in transgenic SOD1G93A mice [ 82].

Engineered cartilage based on adult mesenchymal stem cells (MSCs) is an alluring goal for the repair of articular defects.

Bone tissue engineering, gene therapy based on human mesenchymal stem cells (MSCs) and silk fibroin biomaterials were combined to study the impact of viral transfection on MSC osteogenic performance in vitro.

Here, we reported a novel adipocyte differentiation assay for small molecule selection, based on human mesenchymal stem cells (hMSCs) transduced with fluorescence reporter gene driven by adipogenic specific promoter - adipocyte Protein 2 (also also namely Fatty Acid Binding Protein 4, FABP4).

Our group has generated previously a LMNA-linked experimental model based on human mesenchymal stem cells treated with a human immunodeficiency virus (HIV) protease inhibitor to induce prelamin A accumulation, which recapitulates the phenotypes observed in biopsies of LMNA-linked lipodystrophic patients [ 23].

The three composites tested were found to have some difference in proliferation and differentiation on mesenchymal stem cells in cultures.

Dr. Darwin J. Prockop, an expert on mesenchymal stem cells who was not involved in the trials, said there were still a lot of unknowns about how the cells work.