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We analyzed samples based on menopausal status to determine if these markers had greater predictive ability in one or the other population of women.
To examine the patterns and differences among sleep and hot flashes based on menopausal status (pre, peri, or post) in breast cancer adjuvant chemotherapy patients before, during, and after treatment.
The patients were divided into two groups, based on menopausal status.
The main analysis of our study was based on menopausal status.
Data were analysed in four groups based on menopausal status and two sets of controls.
Moreover, subgroup analyses were performed based on menopausal status and age.
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To randomly assign the intervention arm to patients, 2 randomization lists are prepared in advanced to accommodate the stratification: one for pre-menopausal participants and one for post-menopausal participants, based on their menopausal status at time of cancer diagnosis.
To eliminate the potential influence of menopausal status, the females were divided into two groups based on the menopausal status.
Control subjects were matched to cases based on age, menopausal status, recent hormone replacement therapy, and blood-draw specific variables (such as date and time of day).
For Northern Sweden Mammary Screening Cohort (NSMSC), women were not initially matched on this factor, and 88% of the cases had at least one control matched on menopausal status (pre- and peri-menopausal combined or post-menopausal).
For females we excluded those without known information on menopausal status and use of menopausal hormone therapy (n = 5,894).
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