The decision context IV aims to establish a strong hypothesis-driven scenario based on mechanistic reasoning with structural analogues, including at least one molecule with markedly different potency.
In contrast to physicochemical ODE models that are based on mechanistic descriptions of the biochemical processes, these logic-based ODE models can be seen as continuous representation of qualitative biological knowledge [ 18].
An agent may be assigned to this category if it clearly belongs, based on mechanistic considerations, to a class of agents for which one or more members have been classified in Group 1 or Group 2A.
Models that are based on mechanistic understanding yet remain within the bounds of data-based parameter estimation can accommodate rigorous and complete error analysis.
Results were interpreted according to behavioral models based on mechanistic understanding of leaching processes.
It is based on mechanistic reaction steps and includes the modeling of the radiation absorption effects.
An account of computation that is explicitly based on mechanistic explanation will be discussed in Section 2.5.
Comparisons with models based on mechanistic views and proposed for vapor phase reaction do not offer better data fits.
Yet, the fact that the American authorities underline its visionary character also demonstrates that this approach, which is based on mechanistic toxicity pathways, is still at its beginnings.
Table 1 shows that there were no significant differences between the number of accurate motors for the High- and Low-Mechanistic groups based on Mechanistic Assessment only.
Thus, the lack of difference between the High- and Low-Mechanistic groups based on Mechanistic Assignment does not weaken the findings relating mechanistic knowledge and strategy use.
