Sentence examples for based on mdr from inspiring English sources

We suppose that combination of unique properties based on MDR inhibition, stimuli sensitiveness (pH sensitive activation of drug), improved pharmacokinetics and increased uptake into the cells made the described polymer micelle a good candidate for investigation as potential drug delivery system.

The classical are based on MDR genes and transporter proteins, all reported to contribute to chemoresistance in PDAC [ 3, 4, 41].

This resulted in the detection of a modest synergistic interaction between AKT3 rs2125230-PRKCQ rs571715 (p = 0.011), as shown in Table 4. Based on MDR, this model was the best two-factor model.

In particular, 3,5-bis(4-chlorobenzylidene)-1-[3-(2-hydroxyethylsulfanyl]propanoyl-4-piperidone 4-chlorobenzylidene -1-[3- 2-hydroxyethylsulfanyl]propanoyl-4-piperidoneevertant properties, cytotoxic potencies and tumour-selective toxicity.

Based on AUC, MDR, at 92.3%, and is slightly better than SVM, 91%.

The GMDR, based on the MDR, is proved to be a useful statistical tool to detect gene-gene interaction [ 36].

Patients from the active and placebo groups are matched in pairs based on presence of MDR Gram-negative bacteria, and disease severity by APACHE II score.

Based on our experiments, MDR appears to be robust to unbalanced data and performs well even when the tumor class distribution is extremely unbalanced.

When susceptibility was not tested and the EUCAST did not provide presumed susceptibility, suppositions were made in the following cases (partly based on the low mediocre MDR situation in the Netherlands [ 21]): Moraxella catarrhalis was considered susceptible to ciprofloxacin.

However, in view of the potentially important role of PZA in treatment outcome of MDR-TB, its unique sterilizing activity, and a considerable proportion of MDR-TB strains that are susceptible to PZA (about 50% resistance on average), we propose to classify MDR-TB based on PZA susceptibility into ZS-MDR-TB and PZA-resistant MDR-TB (ZR-MDR-TB).

MDMDR-3.0.3 is a C++ software tool based on the MB-MDR methodology, achieving good results regarding objectives (1), (2) and (4) [ 22, 23].