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Consequently, estimates based on maximal concentrations and terminal plasma half-lives could overestimate drug exposure.
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d) Implementation of a joint entropy-PCA-based feature selection, based on maximal score.
Liu et al. [ 4] presented a method called CMC (Clustering-based on Maximal Cliques) which also identifies protein complexes based on maximal cliques.
This approach links computationally-efficient deterministic model updating with asymptotic Bayesian inference to provide regularization based on maximal model evidence.
We present a Conforming Delaunay Triangulation (CDT) algorithm based on maximal Poisson disk sampling.
This choice is based on maximal efficacy and reasonable tolerability (Figs. 1, 2).
CMC is a clustering method based on Maximal Cliques.
2. Based on maximal theoretical ethanol yield on available hexoses, in most cases only glucose.
Sampling was based on maximal variation in groups, gender and nationality.
Reverse-pharmacokinetic methods (Brightman et al. 2006) can be used to predict oral doses that would be required to trigger molecular processes, for instance, based on half maximal inhibitory concentrations (IC50) for receptor binding from in vitro assays.
Determination of the relative potency of 6-OH-BDE-47 and BDE-47 based on half maximal effective concentrations requires full dose response curves with similar slopes and efficacy, which is not realistic due to the occurrence of nonspecific effects at high concentrations of 6-OH-BDE-47 and the relatively low potency of the parent compound and consequent solubility problems.
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