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Calculation of plaque volumes was based on manually set measurements of length, width and height of the plaques.
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We are not aware of any software system able to identify FGs that is not based on manually curated set of substructure features, but instead automatically identifies all functional groups in a molecule.
We set them empirically based on manually annotated breast cancer data and found that the CNV detection of MixHMM is relatively robust to these parameters (data not shown).
Quantitative analyses are based on manually selected ground truth data.
Research in the past was based on manually designed screens with minimal software support.
Each algorithm overestimated MBF compared to MBF based on manually defined blood pool TACs.
We developed a simple three-step algorithm that categorizes behavioural state as wake, non-rapid eye movement (NREM) sleep, rapid eye movement (REM) sleep, based on thresholds set during a manually-scored 90-min preliminary recording.
Figure 5 ROC curves based on the manually labeled set.
Factor weights were selected based on comparative analysis and were manually set to 0.5, 0.25, 0.5, and 1.
Peaks were detected by a threshold value from the squared signal, which were manually set based on each velocity of chair.
Due to the fact that neither Pfam [35] nor other resources offer Hidden-Markov-Models (HMM) of all the the eight PKS I domains, they were constructed based on a manually curated set of PKS I protein sequence hosted at PKSDB [27].
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