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Furthermore, most software tools which aid in finding and/or explaining analogies are based on manually assembled databases, which require a large amount of interactive work to be constructed and maintained.
For data on protein isoform sequences, we considered two independent sources – one based on manually curated database of splice isoforms, and another based on computational delineation of splice isoforms from EST sequences.
For function prediction, as mentioned in the Methods section, we built one database based on manually curated protein superfamilies and another based on EC numbers to test if the present structure-based method could help in protein function annotation.
In general, all algorithms yielded high correlation with MBF and CFR based on manually defined blood TACs for at least one chosen implementation.
Quantitative analyses are based on manually selected ground truth data.
Research in the past was based on manually designed screens with minimal software support.
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Functionally important amino acid sites such as active sites and binding sites are based on manually-curated annotations available from UniProt [1] and CDD [6].
Indoor, outdoor static, outdoor walking and in-vehicle travel accounted for 83.4%, 6.1%, 3.3% and 7.2% of the data, respectively, based on manually-classified time activity classifications.
Subsequently, each input gene is assigned to one or more functional MapMan bins based on the manually curated binning of the reference database entries [ 42, 43].
Behavioural traits are based on 209 manually tracked frames.
In this study, we present a hybrid named entity recognizer for Turkish, which is based on a manually engineered rule based recognizer that we have proposed.
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