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However, the rationale behind the choice for 3D above two-dimensional (2D) cultures is poorly systematically investigated and mainly based on mRNA expression and glycosaminoglycan (GAG) content.
Cardioembolic and the large-vessel atherosclerotic stroke have been distinguished based on mRNA expression profiles[16].
For comparison, we include in the supplement a report on the accuracies of classifiers based on mRNA expression.
In summary, eight robust candidate genes have been identified and validated, based on mRNA expression in lung tissue, that are potentially involved in COPD severity.
Kv channel subtypes in proliferating hNPCs as well as in differentiated cells were identified using reverse transcription polymerase chain reaction (RT-PCR) analysis based on mRNA expression.
It should be noted, however, that this conclusion is based on mRNA expression data and further studies are needed to explore the impact of lipoprotein formation on cardiac energy metabolism in vivo.
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In this respect, we emphasize that the interpretation of our data may have a weakness being solely based on mRNA-expression without protein data.
One of the widely used methods for the identification of regulatory miRNAs is based on mRNA microarray expression data.
Their target suggestions are based mainly on mRNA expression levels across a population of samples.
This simplification of the model (Equation 10), based only on mRNA expression values and miRNA ID factor resulted in a correlation coefficient of 0.955.
Based on mRNA profiling and expression of cytokeratin 8, mouse ILC is luminal in character but does not express ER/PR during the later stages of tumor progression.
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