Sentence examples for based on low dose from inspiring English sources

Low dose methotrexate was first successfully used in the treatment of post molar pregnancy gestational trophoblast tumours in 1956 [ 2] and protocols based on low dose methotrexate remain the standard of care at most treatment centres [ 29, 59].

In the present study, we employed oseltamivir as a model drug and demonstrated that PK profiles at therapeutic doses may be predicted using PK modeling and simulation based on low dose PK data.

Our results suggest that a treatment based on low dose intensities of the more active drugs can be administered for a long time with a high level of tolerability, and similar response, time to progression and survival rates to those observed using more aggressive chemotherapy regimens (Douillard et al, 2000; Saltz et al, 2000; Souglakos et al, 2002).

BE was diagnosed based on low dose computed tomography (CT) findings that included dilatation of an airway lumen, rendering it more than 1.5 times the width of a nearby vessel, lack of tapering of an airway toward the periphery, varicose constrictions along airways, and ballooned cysts at the end of a bronchus [ 7].

A protocol based on low doses of MMF decreases the infection rate without increasing the incidence of rejection or graft loss.

Studies were often based on low-dose-rate Cobalt-60 systems.

This modification would be crucial in planning and optimizing therapeutic doses based on low-dose diagnostic data.

Projected targeting indices based on low-dose parameter estimates are shown for both our non-linear Ag-Ab binding model and for a conventional linear model.

Before the use of LGE imaging assessment of myocardial viability using MR approaches has been based on low-dose (5-10 μg/kg/min) dobutamine stress cine MRI [107, 108].

SPECT/CT images, even when based on low-dose CT acquisitions, provide the ability to anatomically define the fissures separating the lobes of the lungs so that lobar function can be assessed semi-automatically from co-registered V/Q images in patients who are candidates for lung volume reduction surgery (Fig. 7b).

The PCI-technology as demonstrated here is based on low-dose single injections of the two drugs needed, i.e. injection of the photosensitizer and the targeting toxin conjugate, prior to the light activation.