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A chromatographic method was developed for an endgroup-based separation of low-molecular-mass poly methyl methacrylate) (PMMA), based on liquid chromatography under critical conditions.
Herein, the metabolic fate of ziyuglycoside II in rats was investigated based on liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (LC-Q-TOF/MS).
Herein we introduced an integrated strategy based on liquid chromatography coupled with mass spectrometry (LC-MS) systems to address such challenges.
In the present study, a methodology based on liquid chromatography with diode array detection (HPLC/DAD) coupled to an electrospray ionization (ESI) interface and a triple quadrupole mass spectrometer for the simultaneous identification of phenolic compounds in fruit juices has been developed.
In recent years, the analysis of veterinary drugs and growth-promoting agents has shifted from target-oriented procedures, mainly based on liquid chromatography coupled to triple-quadrupole mass spectrometry (LC-QqQ-MS), towards accurate mass full scan MS (such as Time-of-Flight (ToF) and Fourier Transform (FT -MS).
Quantitative proteomics, which is based on Liquid Chromatography (LC) and Mass Spectrometry (MS) technologies and can systematically identify and quantify proteins at a proteome-wide scale, has emerged as a novel and powerful methodology to characterize functions of various cell types and tissues in humans (Deng et al., 2011a).
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A previous attempt, based on liquid chromatography-electrospray ionization mass spectrometry, found primarily SOD1 and only traces of other abundant proteins [29].
Here we report a method to profile the alkaloids in RC based on liquid chromatography-tandem quadrupole time-of-flight mass spectrometry (LC Q-TOF-MS/MS).
In a study, a novel steroid hormone metabolomic method based on liquid chromatography-mass spectrometry combined with logistic regression analysis was applied to investigate the steroid hormone disorders and to screen potential urinary steroid hormone biomarkers of early HCC [ 27].
Applying a similar approach that is based on liquid chromatography-tandem mass spectrometry (LC MS/MS), we obtained 5-meC concentration values for S. cerevisiae DNA fully comparable to those reported by Tang et al. (data not shown), confirming the precision of the GC MS technology.
A 'bottom-up' proteomics approach based on liquid chromatography-mass spectrometry (LC-MS/MS) label-free quantitative analysis has been used to identify and compare the expression levels of secreted proteins in the MSC CM at early and late cultivation phases.
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