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Markers were assigned to linkage groups based on linkage supported by two-point LOD scores ≥ 3.0, and later ordered within these groups using multi-point linkage analyses employing a heuristic approach.
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The StyI array employed a SNP set based on linkage-disequilibrium patterns that supported approximately one-sixth genome coverage of the base-pair positions across all the chromosomes rather than coverage of known genes in particular pathways or networks.
Additional filtering based on linkage was applied to avoid potential back mutations among shared SNPs.
"Post-Durban Climate Policy Architecture Based on Linkage of Cap-and-Trade Systems". HKS Faculty Research Working Paper Series RWP12-025, May 30 , 2012
Due to very small sample sizes for some samples, no additional pruning of markers based on linkage disequilibrium was performed.
Fine-mapping the putative chromosome 17q21-22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis.
Fig. 1 shows a scheme on gene identification based on linkage disequilibrium.
Selection criteria were based on linkage disequilibrium measurements between the polymorphisms [53].
We filtered marker pairs based on linkage.
Estimates of recombination rates are mostly based on linkage disequilibrium calculations on the population level.
Linkages between adjacent contigs within superscaffolds were classified into three categories based on supporting evidence: (i) both: linkage supported by both Hi-C scaffolds and hybrid scaffolds; (ii) map: linkage supported only by hybrid scaffolds; and (iii) Hi-C: linkage supported only by Hi-C scaffolds.
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