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In this study, 2 procedures were used to analyze a data set from a whole-genome scan, one based on linkage analysis information and the other combing linkage disequilibrium and linkage analysis (LDLA), to determine the quantitative trait loci (QTL) influencing milk production traits in sheep.
Mapping methods were originally based on linkage analysis, either using crosses of divergent breeds or paternal half sib designs in commercial populations.
Fine-mapping the putative chromosome 17q21-22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis.
By modeling identical-by-descent relationships in multiple related families of canines, Liu et al. [13] derived a random effect model based on linkage analysis to genome-wide scan for the existence of iQTL that affect canine hip dysplasia.
This low-cost GS approach is based on linkage analysis of sparse genome-wide marker loci.
Experimental designs used for mapping QTL in livestock based on linkage analysis techniques generally comprise two or three generations.
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Two tests of gene flow, one based on linkage disequilibrium and a MCMC analysis based on coalescence, suggest that the two species might be exchanging alleles at the per locus.
Therefore, this marker framework will be very useful for marker-trait association studies based on linkage disequilibrium, such as QTL analysis, bulk segregant analysis, or even genetic association studies in the mandarin group, where strong diversity was observed for the mapped SNP markers [ 8].
RK undertook the event-based data linkage of transition events, refined the E strategies based on linkage comparisons, and led the analysis.
This left 121 practices that we believed would be suitable for an analysis based on linkage to problem headings.
We identified 20 practices that were using the system in ways that would be unsuitable for any analysis based on linkage.
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