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Developing capacity for comparative monitoring of population-based outcomes based on linkage of routinely collected administrative data has been identified as a priority.
We evaluated the performance of two N e estimators to detect population declines: the two-sample temporal method and a one-sample method based on linkage disequilibrium (LD).
Based on linkage disequilibrium and association with asthma, eight SNPs and one CpG site were selected for further analyses.
RK undertook the event-based data linkage of transition events, refined the E strategies based on linkage comparisons, and led the analysis.
Based on linkage disequilibrium we estimated an effective population size Ne = 20.3 (90% CI = 15 28).
Study Design: Active retrospective study based on linkage of the nationwide hospital discharge register with individual vaccination records.
Fine mapping is based on linkage disequilibrium (LD) and methods using LD information have now been developed for mapping of QTL.
Mapping methods were originally based on linkage analysis, either using crosses of divergent breeds or paternal half sib designs in commercial populations.
Fig. 1 shows a scheme on gene identification based on linkage disequilibrium.
Selection criteria were based on linkage disequilibrium measurements between the polymorphisms [53].
We used a method originally based on linkage disequilibrium (LD; [62]) to estimate contemporary Ne from individual sampling periods.
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