In future, it may be feasible to develop universal models that correct for sensitivity/specificity differentials of the methods used to test for infection, preferably based on large-scale population surveys which have used both RDT and microscopy for the same individuals with the appropriate quality assurance and external validity.
The FRAX is based on large-scale prospective population-based studies and includes age, gender, body weight and body mass index, a history of fracture, hip fracture in parents, current smoking, excessive alcohol intake, rheumatoid arthritis, glucocorticoid use, and other forms of secondary osteoporosis (Table 1).
UK population 'norms' for mean SF-36 scores have been published, based on large-scale surveys in English populations (Jenkinson et al, 1993; Bowling et al, 1999).
Evidence of effectiveness based on large-scale randomised controlled trials of unselected or unscreened population groups in low-income countries was lacking for presumptive treatment of genitourinary infections and micronutrient supplements, with the exception of calcium.
The study was based on large-scale data linking common chronic conditions from general practice populations to prescription data over a 2-year time period.
This information, based on large-scale survey methodology, will provide critical insight into the potential broad and significant impact of obesity among the European population.
This approach is based on large-scale normative data, and the rating scales are available for parents, teachers, and youth.
However, hypotheses based on large-scale comparative studies using statistical methods continue to be proposed.
Most studies on influencing factors have been based on large-scale quantitative telephone surveys.
This supposition has not been based on large-scale studies of normal newborns.
