The study was based on large-scale data available from 53 general practices in one of the most deprived regions in England and over a long-term time period of 3 years.
The research, based on large-scale data on pesticide use, crop yields, and honeybee losses spanning 11 years, looked at the effects of coating seeds with imidacloprid in nine regions between 2000 and 2010.
The false discovery rate (FDR) [16], ranking analysis of microarray data (RAM) [17], FDR-base methods [17], and optional discovery procedure (ODP) [18] identify DEGs through ranking the statistics of any statistical method based on large-scale data.
Both these parameters were found to increase while going from mesophile to thermophiles to hyperthermophiles, which is in agreement with previously reported trend based on large-scale data analysis [69] [72].
The study was based on large-scale data linking common chronic conditions from general practice populations to prescription data over a 2-year time period.
Consistent factor-analytic results, based on large-scale data, provide convincing evidence in favour of the use of the OHS and its subscales.
The study was based on large-scale data linking chronic disease registers from general practices to accident and emergency episodes and hospital admissions.
Despite the developments described here, the requirements for science based on large-scale data generation, sharing and reuse are still evolving.
Altogether, this work highlights the power of a biomarker discovery approach based on large-scale data generation and unbiased data analysis, followed by robust validation using various independent samples sets.
To more accurately evaluate CRAI of a protease inhibitor and an antibiotic in patients with acute pancreatitis, we performed propensity score analysis based on large-scale data from the Japanese nationwide administrative database.
Based on large scale monitoring data, we aimed at building models able to estimate the risk of stream impairment by many types of anthropogenic pressures from taxonomy-based and trait-based characteristics of diatom assemblages.
