Sentence examples for based on large randomized from inspiring English sources

Based on large randomized controlled trials, there is evidence for a therapeutic benefit of TNF blocking agents in RA, axial SpA and psoriatic arthritis [12 14].

Evidence that chemotherapy improves survival and quality of life in patients with stage IIIB & IV non small cell lung cancer (NSCLC) is based on large randomized controlled trials.

Nevertheless, current treatment guidelines are based on large randomized controlled clinical trials, such as the AFFIRM, RACE, and STAF studies, which had mean patient ages of 70, 68, and 66 years, respectively.

Although intra-articular hyaluronic acid is well established as a treatment for osteoarthritis of the knee, its use in hip osteoarthritis is not based on large randomized controlled trials.

The American Diabetes Association ADAA) changed their target hemoglobin (A1c) level to 7% in recent years based on large, randomized, interventional trials showing that tight glycemic control significantly reduces the risk of developing diabetes complications and, ultimately, the cost of diabetes care (ADA 2005).

To date, robust evidence on the role of propofol based on large, randomized, controlled trials for this serious condition is still lacking [ 136].

Multimodality treatment regimens currently in use are based primarily on large randomized trials that exclusively enrolled women with breast cancer.

This approach gives results based on large numbers of randomized patients, but results are difficult to interpret.

It became very clear to me that there were many submissions for consideration as a Brief Report that were based on large-scale randomized trials, epidemiological studies, or large retrospective data searches.

The so-called evidence-based medicine and the adoption of treatment standards based on large epidemiological studies or randomized controlled trials have significantly hampered the efforts to truly personalize the medical practice.

Since 2005 the US Food and Drug Administration FDA and European Medicines Agency EMAEMA) have approved novel agents targeting the VEGF-pathway for patients with mRCC based on large and well-powered randomized clinical trials.