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To retrieve the sequences of Daphnia ion channel genes, Blast searches were performed based on known human or Drosophila ion channel genes.
We subsequently incorporated this information into the EVD model and threshold human risk based on known human cases instead.
The Daphnia genome (http://wfleabase.org/), NCBI and Uniprot protein database were searched for the Daphnia ion channel gene models based on known human or Drosophila genes.
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We used a second array consisting of 1024 peptides based on known phosphorylated motifs in human proteins found in the Human Protein Reference Database (HPRD) [36] spotted in triplicate again made available by Pepscan Systems Briefly, a panel of known, phosphorylation motifs derived from different signalling cascades were selected from the proteins annotated in HPRD.
Uetz et al. predicted interactions between herpesvirus and human proteins based on known interacting orthologs in model organisms, and co-immuniprecipitation confirmed 68% of their predictions [ 19].
They may create their own algorithms to describe their learning, rather than require humans to program them based on known rules.
We constructed a human PXR (hPXR) pharmacophore model based on known structural information of compounds that activate PXR.
Thus, although based on the known human miRNA targets, the target prediction algorithm should reveal all functionally important targets which are fully conserved across species.
Two types of SAGE tag reference databases were used, including the SAGEmap full database that contains annotated SAGE tags based on the known human transcript sequences (http://www.ncbi.nlm.nih.gov/projects/SAGE/) and the GEO SAGE database that contains experimentally collected SAGE tags (http://www.ncbi.nlm.nih.gov/geo/).nih.gov/geo/
One project was based on known technology.
It is based on known information.
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