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We studied the distribution of protein families among C. elegans TFs based on known DNA binding domains.
CRMs can be detected using ab initio discovery of new (e.g. Gupta and Liu, 2005; Zhou and Wong, 2004) or based on known DNA motifs.
This approach may not be applicable to SNP studies but would apply to design of ligands based on known DNA sequences.
Similar(57)
These enzymes were chosen because they were expected to discriminate between each of the seven non- rep DNAs based on known sequence information from the Syrian and Egyptian isolates of FBNYV and the Ethiopian isolates of FBNSV and MDV.
However, STAMP as well as footprintDB detect and predict TF-DNA interactions based on known data.
Based on known phage mutation rates, this piece of viral DNA seems to have dispersed sometime in the past 2,000 years5.
It is based on known information.
Antibodies were selected based on known performance.
These matrices were based on aligned motif sequences of the known DNA binding sites from the members of every transcriptional module.
A new surface patch is predicted to be interface or non-interface patch based on its similarities to known DNA-binding patches and non-DNA-binding patches.
Genes were grouped into different families based on the presence of known DNA-binding domains according to the WormBase [ 14], Pfam [ 68], and InterPro [ 70] databases.
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