Sentence examples for based on known data from inspiring English sources
The most commonly applied VS methods are molecular docking, pharmacophore identification and ligand similarity (including shape based), along with a variety of machine learning methods that "learn" to differentiate actives from inactives based on known data [18, 19].
Based on known data about the behavior of the sound transmission mechanism, we generate a model that reproduces the real mechanics of the middle ear by the finite elements method in the most exact manner possible.
However, STAMP as well as footprintDB detect and predict TF-DNA interactions based on known data.
Determination of the required sample size is based on known data from the previous FAMS study [ 8, 26].
The first example is based on known data generating processes to avoid uncertainty about true model, virtually inevitable for empirical data.
Additionally, Monte Carlo methods are amenable to biasing the sampling space based on known data to improve results; however, this is expected to incur a corresponding cost in convergence time.
This is likely to be because BayesTraits first identifies the best predictive model based on known tip data to then infer unknown ancestral states at each node of interest in the tree and can incorporate evolutionary trends.
Construction of gene networks based on known cellular pathways and expression data from our analysis demonstrated that the network associated with cell death, cell cycle regulation and DNA replication and repair was most heavily affected in this model of disc degeneration.
The imputed data are predicted based on known information of each individual [ 25].
One could also adjust the prior based on known genotype data, or use the posterior probability that d > 0 as a measure of evidence for allele-specific methylation.
Furthermore, a population pharmacokinetic model can be used to assist with dosage adjustments by using Bayesian revised dosage predictions based on known concentration time data in each individual 5. Numerous population pharmacokinetic models have been developed to characterize the pharmacokinetics of tacrolimus in adult kidney transplant recipients 6– 16.
