The logical workflow of each production task is organized based on knowledge base, and then turned into the actual executed workflow by Kepler.
During the past 20 years, North Carolina has transitioned from an economy driven by tobacco and textiles to one based on knowledge-based enterprises like software, IT, financial services, and film and TV production.
An approach to a CAD/CAM system is based on knowledge-based rules.
An approach to the computer-aided process planning system is based on knowledge-based rules and a process knowledge base consisting of design rules is built.
Now PAT paves the way for continuous process and product improvements through improved process supervision based on knowledge-based data analysis, "Quality-by-Design -concepts, and, finally, through feedback control.
Towards this goal, we have developed a novel framework, called Discovery Informatics, that is based on knowledge-based systems, statistical machine learning, neural networks and genetic algorithms, for the rapid discovery and design of new materials such as fuel additives, rubber compounds, polymers, catalysts, and nanomaterials.
Based on knowledge-based rules, the system is designed by considering several factors, such as the material and thickness of product, the complexities of blank geometry and punch profile, the diameter and material of a wire, the working conditions, and the availability of a press.
These scoring functions are based on knowledge-based atom-pair potentials which can be used in an additive manner (PMF-Score) to score protein-ligand complexes.
The strengths of hydrophobic contacts, π-π interactions, and cation-π interactions are based on knowledge-based potentials [33] in which each individual interaction has a score between 0 and 1.
Previous research has investigated growth strategies based on knowledge-based innovations resulting in new practice developments (Anand et al. 2007), internationalization (Aharoni 1993), and the exploration of new regional markets (Reihlen et al. 2009), as well as growth opportunities through mergers and acquisitions, and alliances (Kaiser and Ringlstetter 2011).
