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This conclusion is based on kinetic studies of HIV-1 replication during the primary antigen specific CD4+ T cells in vitro where R5 virus growth was selectively dampened by the synthesis of anti-viral CCR5 ligands by the responding T cells.
Several competing models for the catalytic mechanism of SCS have been proposed based on kinetic studies.
Based on kinetic studies, this increased fecal loss appears to be secondary to an interrupted enterohepatic circulation of bile acids [ 20, 21].
Goh et al. tested plated femora using 20%, 40%, and 60% of body weight to simulate progressively increased weight bearing in the early postoperative period, using values based on kinetic studies in dogs [ 20, 21].
Pol δ was shown to have high selectivity for the correct nucleotide based on kinetic studies of the insertion of individual dNTPs opposite a known nucleotide in a DNA template.
Based on kinetic studies, argininosuccinate synthesis was initially postulated as a key urea cycle control node [ 41], although normal urea cycle operation is assumed to rely more on other parameters such as pH, ammonium availability, and N-acetyl-glutamate levels [ 42].
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In the present work, a plausible reaction network based on kinetic study of the hydrodeoxygenation of HMF over a carbon-supported nickel catalyst is proposed.
We have solved the molecular mechanism of the formation of shish of isotactic-polypropylene (iPP) and polyethylene (PE) from the sheared melt based on kinetic study by means of polarizing optical microscope.
These results questioned the results of Schrimsher and Taylor who proposed, based on kinetic and inhibitor studies, that NADH binds first followed by a random binding of L-arginine and pyruvate [12].
The large amplification of ee observed in this autocatalytic reaction is often explained by the formation of aggregates, which has been proposed to account for the positive nonlinear effect observed during asymmetric catalysis.[ 11] Mechanistic studies based on kinetic experiments,[ 12] reaction modeling,[ 13] NMR,[ 14] and DFT calculations[ 15] have been examined by several research groups.
Although researchers have published many studies on the design of metabolic systems based on kinetic models and optimization strategies, almost no studies discuss the multi-objective optimization problem for enzyme manipulations in metabolic networks considering resilience phenomenon.
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