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Based on kinetic modeling, the PET-derived protein synthesis rate was comparable to simultaneously conventional stable isotope measurements [32].
By applying a systems biology approach in which we combined results obtained from metabolic control analysis based on kinetic modeling with data obtained from quantitative metabolite profiling and enzyme activity analyses, we could provide new insights into metabolic and kinetic interactions contributing to the control of carbon flux from xylose to ethanol.
In this work, we could demonstrate that integrating data obtained from metabolic control analysis based on kinetic modeling, quantitative metabolite profiling and enzyme activity analysis represent a powerful approach to identify metabolic and kinetic interactions that play an important role in controlling the key process parameters, qxylose and Yxylitol.
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Several approaches based on kinetic models [5, 6] have been proposed earlier to assess the renal clearance of FDG.
Regional distribution volumes (V Ts) were calculated based on kinetic models with and without considering radiometabolite in the brain.
Reactor design and operating conditions are based on kinetic models developed under isothermal conditions in micro-structured reactors.
Hence, we examined maturation profiles of organic matter derived from sedimentary rocks and attempted to reconstruct the burial history based on kinetic models.
Based on kinetic model equation, a unified gas-kinetic scheme for axisymmetric flow (UGKS-AS) is proposed in the whole flow regimes.
The variation in aggregate diameter and concentration with time has been mathematically described, based on kinetic models (first-order for diameter, first- and second-order for concentration), derived from several theories and correlations previously applied to the formation and disruption in different aggregate systems.
Simulations of other cellular systems, such as signaling networks and membrane electrophysiology, are also based on kinetic models for mechanisms of relevant individual enzymes and transporter proteins.
Simulations based on kinetic models can help develop in-lab strategies, thus increasing the success rate of metabolic engineering.
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