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For subsequent analyses, we used the most high-confidence regions (FDR < 0.01) based on joint p-value score and fold enrichment cutoffs of 500 and 20.
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The significance of gene expression changes was inferred based on an adjusted p-value (q-value) <0.1.
We chose the model based on the p-value.
Each class was grouped based on their p-value.
Portilla, J. & Simoncelli, E. P. A parametric texture model based on joint statistics of complex wavelet coefficients.
IQR = inter quartile range; FFbH = Hannover Functional Status Questionnaire measuring functional capacity in percent of full function; DAS28: disease activity score based on 28 joint counts; # = P-value for comparison between biologic and control group within strata according to prior malignancy status,.
Enrichment/depletion was calculated based on p-value corrected using the false discovery rate (FDR).
Based on joints works with I. Pak, C. Ikenmeyer, P. Bürgisser.
This results in inference based on corrected p-values.
Based on these P-values, we derive the 'true' network.
The probe sets were filtered based on detection p-values.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com