We have chosen the HICF fingerprinting method based on its well-established format with a commercially available SNaPshot labeling kit (ABI) and increased throughput using the ABI 3730 xl sequencer [ 17, 21].
Finally, to demonstrate the utility of the EPTA stain beyond simply detecting synapses, we used shape features to characterize the strength of each synapse based on its well-established correlation with spine size (Lee et al., 2012).
Based on its well-established use as a lipid-lowering agent and efficacy when combined with many antidiabetes and/or lipid-lowering therapies, colesevelam may be an appropriate agent for use throughout the type 2 diabetes continuum, including in high-risk patients (with prediabetes) as well as late in the disease.
The clinical skills assessment and its marking is based on a well established pedagogy that is internationally recognised and used widely in postgraduate examinations.
The mechanism of pH-triggered release from nanocarriers based on polyelectrolytes was well established based on previous reports.
This is based on the well established fact that surface stress is directly proportional to the surface charge density [14].
Stress mapping is based on the well established method of measuring shifts in the characteristic optical fluorescence lines produced by Cr3+ impurities in the alumina matrix.
Furthermore, the new model is based on the well established methods of calculation for the equilibrium stage and mass transfer efficiency.
It thereby demonstrates the usability of a theoretical framework which is based on different well established methods and guidelines and specifically adapted for economic evaluations of primary preventive physical activity programmes [11].
Our work indicates that CX3CL1 and GM-CSF may represent putative biomarkers of inflammation associated with atherosclerosis, such as C-reactive protein, but are mechanistically tied to atherosclerosis based on the well established findings in animal models of atherosclerosis.
Strategies to manipulate calcite precipitation in the subsurface for the purpose of sequestering 90Sr are based on a well established understanding of the kinetics of low temperature calcite precipitation and dissolution [5 11] and of Sr2+ partitioning into calcite [12 21].
