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In every steps of serial virtual screening, one candidate was estimated and ranked based on its influence on the network efficiency of clotting cascade network instead of the scoring functions of these binding poses on one target as used in conventional virtual screening methods.
South Africa's role is based on its influence on the continent," notes Dr Petrus de Kock, senior researcher in the "Governance of Africa's Resources" programme at the South African Institute of International Affairs, a research organisation in Johannesburg.
Although the role of Fabp7 in fatty acid delivery during development is not clear, its involvement in cell growth and differentiation has been implicated based on its influence on cell morphology [3].
In contrast, interRAI assessments focus on functional implications such that impairment to the eye would be captured based on its influence on a person's functional vision.
Most knowledge about the molecular and cellular bases for the pathogenic effects of HCMV is based on its influence on the pattern of host cell gene expression [ 17, 29].
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Second, we tried to assess the longer-term opportunities a company has based on its current influence, the strength of its competitors, how much influence government policy will have on its success, and how likely it is and how quickly the company's products can be implemented at a reasonable scale.
More generally, since under most conditions the actual and environmentally-expected states are compatible, it is difficult to discern whether gene expression is regulated predominantly by an internal feedback-mechanism, or whether it is tuned by an environmental signal based on its expected influence on the internal state.
16 Acupuncture may positively affect the pathophysiology of ED based on its homeostatic influence on the autonomic nervous system.
Reach is summarised for each mention as a score between 0 and 10 based on its authority and influence.
A weight is assigned to each condition based on its potential to influence 2-year mortality, and these weights are summed to obtain an index for each patient.
Based on its ability to influence miR-26b [ 74] and the transcription factor CREBBP [ 75], dexamethasone was considered as a repurposing candidate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com