Sentence examples for based on its important from inspiring English sources

Based on its important physiological role it has been of interest to design pharmacological tools to module Cx43 synthesis, assembly, stabilization or degradation.

Thus, based on its important pro-angiogenic effect, we hypothesized that PAI-1 may regulate lymphangiogenesis associated at least with metastatic dissemination of cancer cells.

In recent decades, several previous studies have confirmed that the elevated COX2 levels may be an indicator of biologically aggressive tumor prognosis based on its important role on tumor cells growth and metastasis [ 21, 22]; meanwhile other studies have also illustrated inconsistent results [ 8, 23].

Of the seven protein-coding genes and one miRNA gene present in the minimal common region of the same amplicon, the TrkA gene was the most promising candidate for driving segmental amplification within the 1q23.1 region in MM, based on its important role in melanocyte biology and known involvement in cancer.

7 8 Several recent studies have indicated that an increased serum PAPP-A level may be a biomarker of EH and HDP based on its important effects on the proliferation of vascular smooth muscle cells, and on the reconstruction of extracellular matrix.

The non-official body first gave the capo the title in 2013, based on its role as an important US distribution centre for his cartel's drugs, but removed it after his capture the following year.

Designing a network with given functions or reconstruct a network based on its dynamical behavior is an important problem in the study of complex systems.

Thioredoxin glutathione reductase of Schistosome japonicum is a membrane protein of about 65 kDa, which is considered as a promising vaccine candidate antigen based on its immunogenicity [ 29] and its important role in parasite metabolism as a vital enzyme to balance redox equilibrium [ 34].

In fact, the model now rates Wisconsin as the fourth-most important state based on its tipping point index, up from tenth place before, and trailing only Ohio, Florida, and Virginia.

Each particle selects a set of important features based on its position string.

Israel's policy should not be based on what its most important ally wants, but on what it believes will bring the peace and security it has always sought.