Sentence examples for based on its high level from inspiring English sources

Therefore, based on its high level of sequence homology to other human immunoglobulins, the sequence of the antibody moiety of InO is not expected to confer increased risk of immunogenicity relative to other monoclonal antibody therapeutics.

This species has a fragmented geographic distribution that could be subdivided into different meta-populations based on its high level of genetic differentiation [ 8- 10].

chose the promoter based on its high level, and β-cell-enriched, expression in driving insulin-like growth factor 2 (Igf-2) and glucose transporter 2 (Glut-2) antisense gene expression (Valera et al., 1994; Devedjian et al., 2000; Guo et al., 2005).

Under the safeguard mechanism, government agency the Clean Energy Regulator sets an emissions limit for each large industrial site based on its highest level of emissions over the previous five years.

Based on its high expression level in TMZ-resistance cells, Na+/K+-ATPase may be a therapeutic target for the treatment of glioblastoma and sensitizing glioblastoma cells to conventional chemotherapy.

A third likely pathogenic mutation was a homoplasmic MT-ATP6 variant m.8954T>C (haplogroup H4a) for NonCM6 with LHON based also on its high level of conservation (CI=0.77).

The hPAB-β trimer construct was selected out for the subsequent study based on its higher expression level (27.8%), which yields in wet cell weights (3.15 ± 0.45 g/l) and the fusion protein inclusion bodies was able to completely dissolve in 8 M urea.

We selected integrin β1 as a HNSCC target based on its reportedly high level of expression in this cancer type.

Oral vancomycin was recommended only for the most severe cases and for those relapsing after a course of metronidazole, based on its extremely high faecal levels, which are several hundred times higher than the MIC90 of vancomycin against C. difficile.

Given that our classification seeks to capture the diversity of physical and natural attributes of islands, the most appropriate classification is one based at its highest level on lithology and elevation.

Restriction in the use of the B-cell V gene was shown to have a direct clinical impact in CV patients, based on its association with higher levels of rheumatoid factor activity and with lymphoproliferative disorders [ 12, 13].