Sentence examples for based on its essential from inspiring English sources

Based on its essential role in the life cycle of Trypanosoma cruzi, the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH) has been considered a promising target for the development of novel chemotherapeutic agents for the treatment of Chagas' disease.

Fuons are defined as an abstraction of a product, based on its essential function and representing the whole set of products that share the parameters for this function's flows.

Next, we studied the role of TBX3 in CSCs based on its essential role in embryogenesis and stem cell function 30 as well as its implication in oncogenic processes.

Our new data strongly suggest that, likely based on its essential role in driving inflammation, mPGES-1 may be considered a novel target that might be useful in slowing the initial, rapidly progressing, inflammatory phase of SSc that is required for the subsequent development of fibrosis and therefore may be useful in a stage-specific modulation of the pathogenesis of SSc.

As shown in Fig.  1a, we selected to target phenoloxidase gene based on its involvement in several essential steps in the melanin synthesis pathway [ 52, 60].

The World Health Organization has approved ribavirin for use for CCHF and has added the drug to the essential drug list, mainly based on its in vitro effect (reference WHO Essential drugs submission) [ 55].

It was based on one essential idea -- any and all regulation is evil.

In a time when marketing is king, the fortunes of Pixar, now owned by Disney, have risen or fallen based on the essential quality of its films.

The embrace of digital marketing so far is largely based on two essential factors: it's effective and it's easy.

Its program would be based on the essential political logic: If you want to get anything passed, you have to offer an intertwined package that smashes the Big Government vs. Small Government orthodoxies and gives everybody something they want.

He embraced a view of the world based on an essential excitement that it should exist at all.