Although at first sight Shigella would seem to be an unlikely candidate as a therapeutic agent based on its pathogenicity, the fact that attenuation was readily achieved and that a small number of bacteria at the tumor site was sufficient to induce a dramatic anti-tumor effect suggests that further investigation is warranted.
Images were reconstructed using a filtered backprojection algorithm, with a dual-window scatter subtraction combined with either no attenuation compensation or single iteration Chang attenuation compensation based on an uniform attenuation map (mu = 0.152 cm-1) or the nonuniform transmission map.
Standard attenuation and scatter corrections were performed based on MRI-derived attenuation maps, complemented by emission-based attenuation data in areas not covered by MRI.
The reconstruction was performed with 2.54-mm cubic 256 × 256 matrices, integrating a scatter correction using dual-energy scatter window subtraction and an attenuation correction based on attenuation maps derived from CT data.
Flash3D is an ordered subset expectation maximisation (OSEM) reconstruction algorithm with depth-dependant 3D (axial and trans-axial) resolution recovery, scatter correction using scatter window subtraction (dual energy window approach) and attenuation correction based on attenuation maps derived from the CT data filtered with the B08s kernel.
SPECT reconstruction was performed using Flash3D [15, 16] 16], an ordered subset expectation maximization (OSEM) reconstruction algorithm with depth-dependant 3D (axial and trans-axial) resolution recovery, scatter correction, and attenuation correction based on attenuation maps derived from the B08s CT data.
Surface karst features, such as enclosed depressions, were reclassified based on P attenuation potential in soil at the base.
The measurements of the variation in the concentration of the fine particles were performed by means of a photo-detection technique based on the attenuation of light.
In contrast to previous research, our results indicated that estimates based on the attenuation difference appeared poorer than the estimates based on individual frequencies.
