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It turned the negative sentiment into largely positive sentiment based on its activity on Twitter.
Based on its activity in these assays, the W290H-W308F W-less RecA was purified for in vitro characterization and functioned like WT RecA in DNA-dependent ATPase and DNA strand exchange assays.
Thus, beneficial effects of GM-CSF-driven tolerance in CD seem somewhat counterintuitive, as GM-CSF is generally regarded as a cytokine with more proinflammatory functions based on its activity on neutrophils and macrophages.
The treatment dose for the nanoworm construct was chosen based on its activity in vitro.
The dose of ACA was selected based on its activity in previous dietary studies [ 31- 34].
(5, 6, 13) Based on its activity in preclinical models involving human cells, 5, 6, 13) olaratumab entered clinical development.
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The predictability of V$E2F_03 to patient survival is also revealed by the survival curves of the two patient groups based on its activities as shown in Figure 1B.
In the 1990s, thalidomide (Thalomid®, Celgene Corporation) was used empirically in treatment of MM based on its antiangiogenic activity and clinical activity in refractory or relapsed myeloma [6].
While toceranib was approved based on its demonstrated activity against canine mast cell tumors (MCT), activity against various other tumor types has been documented including several types of carcinomas [ 1, 3, 6].
The recognition that thalidomide was active in myeloma was based on its antiangiogenic activity in in vitro models together with the unexpected description of neo-angiogenesis in the bone marrow of myeloma patients.
We show that HoBGLA is an attractive candidate for industrial lactose conversion based on its high activity and stability within a broad pH range (4.5 7.5), with maximal β-galactosidase activity at pH 6.0.
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