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The PK and PD parameters were calculated by non-compartmental analysis using Phoenix WinNonLin software (Pharsight, Sunnyvale, CA, USA) based on intensive data.
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Tesco's United States strategy is based on intensive market research.
Therefore, further prospective studies based on intensive designs are needed.
At present, most interventions in pregnancy are based on intensive maternal and fetal monitoring.
However, intensive data collection based on intensively observed smaller sample sizes is emerging in many areas of behavioral and health research in aging and beyond and many innovative statistical procedures have been suggested to optimally treat such a data situation [ 74, 75].
Interviewees stated that researchers usually want to publish several articles based on one data set because randomised controlled trials (RCT) tend to be very resource and time intensive.
The availability of big data is revolutionizing how research is conducted and is leading to the emergence of a new paradigm of science based on data-intensive computing and analytics.
We aimed to develop and validate two predictive models for one-year mortality in patients with AKI based on data (1) on intensive care unit (ICU) admission and (2) on the third day (D3) in the ICU.
Based on a data-intensive weather-driven modelling approach, technically and economically optimal designs are derived for a simplified, highly renewable pan-European electricity system, which minimise the need for backup energy, backup capacity, transmission capacity and the levelised system cost of delivered electricity.
Treatment targets and algorithms were common for the intensive treatment group in all centres and were based on trial data demonstrating the benefits of intensive treatment of cardiovascular risk factors in people with Type 2 diabetes [ 1, 2, 24– 26].
"Based on this intensive, three-year data collection effort, Deepwater Wind believes that there are no environmental impediments to building and operating the wind farm and transmission cable in the designated locations," the company said in a statement.
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