In addition to those based on intensity ratio and average intensity (MARS), two other methods were employed to evaluate differential expression: Fisher's exact test and Likelihood ratio test.
By considering a heterogeneous set of features, e.g., statistical descriptors, spectral measures, and morphological descriptors, AdaBoost classifier based on intensity channel achieves the best average performance.
We partitioned the Xl-PSIDs into equal tally and equal intensity deciles based on average intensity values in order to facilitate data analysis.
The top three up-regulated protein-coding genes (DUOXA2, CHI3L1 and CXCL9) and lncRNA genes (MMP12, FAM66D and SAA2-SAA4) showed increasing signal intensity based on the averaged gene expression levels across the spectrum of clinical subgroups from control to iCD and iUC (P-value < 0.001; Figure 2C).
22 Probe sets were collapsed based on average intensity values.
In the cases where cell somas were imaged (vPN1 imaging), fluorescence videos were segmented based on average intensity using k-means clustering, following which individual cell bodies were labeled as different region of interests.
To study the effect of different CRRT intensity on clearance of urea and creatinine, all patients/daily observations were arbitrarily allocated to one of 4 groups based on the average intensity and daily intensity: <10, 10 15, 15 20, and >20 mL/kg/h.
To study the effect of different CRRT intensities on clearance of urea and creatinine, all patients/daily observations were arbitrarily allocated to one of four groups based on the average intensity (patients) and daily intensity (daily observations): <10, 10 to 15, 15 to 20, and >20 mL/kg/h.
The studies cited above use methods that pool spots together based on their average intensity or logged intensity.
In addition to the proportion score, an intensity score was made based on the average intensity of staining, 0 = negative, 1 = weak, 2 = intermediate and 3 = strong.
