Sentence examples for based on inhibition of from inspiring English sources

The observed weaker in vivo potency and efficacy of EGCG in inhibiting L-DOPA methylation (based on inhibition of 3-OMD formation) likely are due to its relatively low oral bioavailability in rats (only approximately 2%) [36], [37].

The anti-Xa assay detects heparin in patient plasma based on inhibition of Factor X in an assay reagent.

Immunotherapy based on inhibition of PD-1 or PD-L1 represents a breakthrough in the treatment of advanced cancers, particularly lung, renal, and melanoma cancers.

These findings could provide a rationale for designing new therapies based on inhibition of hepatocellular carcinoma (HCC) angiogenesis.

An SAR was established based on inhibition of CCR5 (RANTES) binding and these compounds exhibited potent inhibition of R5 HIV-1 replication in peripheral blood mononuclear cells.

Using an assay based on inhibition of binding, PEG2000-PE transfer from donor liposomes to biotinylated acceptor liposomes could be measured.

In addition, the efficacy of siRNA-induced gene silencing can only be experimentally measured based on inhibition of the target gene expression.

The observed anti-cancer activity based on inhibition of microtubule formation may be helpful in designing more potent compounds with a hexahydropyrazole moiety.

Rational conversion of noncontinuous active regions of proteins into a small orally bioavailable molecule is crucial for the discovery of new drugs based on inhibition of protein protein interactions.

Here we discuss the therapeutic approach based on inhibition of angiogenesis in the context of breast cancer with a focus on the early clinical studies on antiangiogenic agents in advanced disease.

The mode of action of ACE is mainly based on the inhibition of synthesis of prostaglandins (PG).