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The value of α can be adjusted from 0 to 1 based on individual datasets; the smaller the weight, the less the tumor volume is constrained (please see the 'Discussion' section for more comments on this technical point).
The first approach is based on individual datasets.
Tracks based on individual datasets are shown separately, as well as the consensus HapMap track.
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First, most previous work on drug response prediction mainly based on individual dataset, such as NCI60, CCLE or CGP, but seldom see integration analysis.
Due to the lack of data available, micro analysis based on individual, household or local datasets are limited to small parts of Africa [ 23].
Our method is better at differentiating prognosis based on individual pathway activation than the approach employed by Bild et al. for a human ovarian cancer dataset.
Finally, a bonus based on individual performance.
Abacus' profiles are based on individuals.
Different from this type of descriptive accounts of aggregated data, analytical epidemiology is about aetiological hypotheses testing and statistical inference based on datasets with individual level records that allow control for confounders.
It is based on a dataset containing individual records for the 4800 individuals in the CCF, with variables indicating E and O status, as well as the above-mentioned sampling weight.
More specifically, phylogenetic reconstructions based on concatenated datasets do not account for individual gene histories, and can therefore produce misleading topologies, with most of the nodes highly supported (high bootstrap values and/or posterior probabilities) despite their not reflecting the actual evolutionary history of the species [ 52- 56]; but see also [ 57].
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