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An efficient gene-targeting system based on impairment of the nonhomologous end-joining pathway and the orotidine monophosphate decarboxylase gene (pyrG) in Aspergillus flavus was established.
During the design process choices without supporting evidence had to be made, this is because treatment based on health status is a novel concept and all previous studies were based on impairment of lung function as treatment criterion.
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Instead, many studies provide indirect evidence based on impairments of chemical synaptic transmissions by Aβ [7], [13], [38].
However, little is known about the extent to which different subregions of the prefrontal cortex are required for specific aspects of decision-making, based on impairments of particular aspects of behavior by focal damage to subregions of the prefrontal cortex.
Table 2 describes the univariate odds ratios for presence of social role restriction (yes vs. no) based on impairment categories and type of activity limitation.
The final two demonstrations were geared toward subgroups of beneficiaries based on impairment type (psychiatric disabilities) and age (young adults).
The proposed model is based on impairment factors which quantify the quality-impact of the different degradations.
In other mammals, the diagnosis of albinism is based on the impairment of tyrosinase production through defects in the Color (C) gene.
HACA produced three sites groups based on the impairment of sites.
Thus, before cancer therapies based on functional impairment of flotillins are developed, it will be important to clarify the crosstalk between flotillins and oncogenic mutations that are frequently found in specific cancers.
It has been suggested that the impact of child or adolescent obesity on HRQL is influenced by culture [ 3], but since the evidence base on impairment of HRQL in adolescents is still very limited in geographical scope the hypothesis that culture influences the obesity associated impairment of child or adolescent HRQL has not been tested.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com