Sentence examples for based on immune checkpoint from inspiring English sources

One is based on immune checkpoint inhibitors, the type Carter received, which take the brakes off of the immune system.

With the advent of immuno-oncology drugs based on immune checkpoint blockade, a clear rationale for synergy between the two approaches, and initial pre-clinical and clinical data suggesting this to be the case, it might be expected that oncolytic immunotherapy combined with checkpoint blockade will provide a cornerstone of future cancer treatment.

However, even a modest degree of COX inhibition might help enhance the efficacy of immunotherapies, including those based on immune checkpoint blockade.

"Almost everything we know about infection is based on immune response studies and looking at how the immune system eliminates pathogens (harmful agents)," said Medzhitov.

Therapies based on immune cells have been applied for diseases ranging from cancer to diabetes.

Lastly, we will review the current understanding of mechanisms employed by brain tumors to evade immune detection, with a focus on immune checkpoint pathways.

Dr. Naiyer Rizvi, director of thoracic oncology at CUMC, offers updates on immune checkpoint inhibitors in certain forms of lung cancers.

Clinical responses and safety data reported to date on immune checkpoint inhibitors suggest these agents may have the potential to markedly improve outcomes for patients with cancer.

However, the effect of environmental carcinogens on immune checkpoints needs to be elucidated.

This volume reviews the current state of research on immune checkpoints and offers novel concepts.

Intense interest in cancer immunotherapy has focused recently on immune checkpoints, whose function to dampen immune responses is important for self tolerance and control of physiological immune responses.