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Based on identified subpopulations we hypothesize the following structures for a p-coumarate degrading consortium and a benzoate degrading consortium.
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Zoonotic diseases are responsible for the majority of emerging infectious diseases [ 29], and improved understanding of disease ecology would provide an evidence base to guide the development of tools to help predict the timing and triggers for outbreaks, determine hotspots based on environmental factors, identify subpopulations who are at greatest risk.
In this MLM (Q + K model) described previously, the population structure matrix (Q) was identified based on the significant subpopulation structure in this association population (K = 11) (Du et al. 2012).
Therefore, flow cytometry analysis was used to identify subpopulations of cells based on Oct4-GFP+ and SSEA1− status, in addition to a low intensity of GFP expression.
This can be accomplished using unsupervised learning techniques to identify subpopulations of individuals based on indices of brain function and then identifying their associated phenotypes, as illustrated in Figure 2 [ 80].
In 2012 FDA issued a draft guidance to facilitate enrichment design, where it pointed out the uncertainty on the subpopulation classification and on the treatment effect outside of the identified subpopulation.
We believe this first analysis must necessarily address the universe of alcohol outlets before parsing out effects based on subpopulations.
Based on competition among subpopulations with different mutation rates, we investigated the evolution of mutation rates in finite asexual populations.
The detailed analysis of our study was based on this subpopulation.
The initial QTL analysis was conducted based on the subpopulation.
In this study, birth weight is standardized (Z-scored) for each subpopulation based on the subpopulation specific mean and variance.
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