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We used Fisher's exact right-side test based on hypergeometric distribution and corrected for multiplicity testing by the Bonferroni method.
We calculated the probability values based on hypergeometric distribution instead of chi-square distribution, which is used in the original ACME.
Based on hypergeometric distribution, we carried out a function enrichment analysis between the progression-related sub-network and the whole human biological network.
For cellular pathway analysis, MetaCore is based on hypergeometric distribution, SAM-GSA uses "Maxmean" statistic, and GSEA uses modified Kolmogorov-Smirnov statistic.
P values were calculated based on hypergeometric distribution analysis.
Methods based on hypergeometric distribution, if properly implemented, are also fast.
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Significant enrichments of GO terms were computed based on hypergeometric distributions using FUNC [ 80] by comparing the numbers of a given GO term in the target group with the numbers in the background group.
The p-value was calculated based on hypergeometric cumulative distribution function.
The widely used count-based methods are based on the hypergeometric distribution or other similar probabilistic models (Cho et al., 2001; Huang et al., 2009; Khatri and Drăghici, 2005; Man et al., 2000).
In contrast to these sample-independent overrepresentation maps based on the hypergeometric distribution one can use the GSZ-score (Eq. (10)) to study metagene-related gene set enrichment in a sample-specific fashion.
The motivation of our approach is that methods that count shared metabolites, or methods that generate a p-value for shared metabolites based on a hypergeometric distribution, essentially assume a flat degree distribution for metabolites.
More suggestions(13)
based on allelic distribution
based on square distribution
based on content distribution
based on random distribution
based on binomial distribution
based on uniform distribution
based on centralized distribution
based on hypergeometric analysis
based on hypergeometric test
based on intrahousehold distribution
based on geographic distribution
based on spatial distribution
based on continuous distribution
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