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Desferal, deferiprone and deferasirox, chelating agents nowadays in use, are based on hydroxamic groups, hydroxyl-substituted pyridinones or aromatic ring systems.
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Here we present a successful optimization study of tubastatin A, the synthesis and biological evaluation of new inhibitors based on hydroxamic acids linked to various tetrahydro-β-carboline derivatives.
To date, a large number of MMP inhibitors based on hydroxamic acid derivatives or other synthetic inhibitors have been designed.
Wealth: $190 million, based on the group's 1999 net assets.
Wealth: $146 million, based on the group's 1998 net assets.
loves sharing discussion based on common group experiences.
Two types of node groups are considered: groups based on physical proximity and groups based on modal sensitivity.
All based on group analyses.
Parts are combined based on a part group dictionary.
Fig. 1 Temporal acid-base variation based on group.
Quartiles based on the control group.
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