Sentence examples for based on human gene from inspiring English sources

To confirm this expectation, the author first calculated the expression similarity of pairs of interacting genes in the CCA network based on human gene expression data presented by Su et al. [20] by Pearson's correlation, which is frequently used to calculate gene expression similarity (see Materials and methods).

In total, 440 genes with a biological role in reproduction were identified in the dataset based on human gene names.

Gene-specific PCR primers located within exons or spanning exon junctions were designed based on human gene sequences obtained from Ensembl http://www.ensembl.org/.org/

The GiSAO database established in the current communication focuses on genetic regulation of aging at the cellular level, based on human gene expression data, and allows the identification of evolutionarily conserved regulators of cellular aging.

As an example of comparisons between closely-related species, our pipeline was first applied to generate human-chimpanzee orthologous genes based on human gene annotation (Ensembl v64) [ 4], human reference genome (hg19) [ 17], and chimpanzee reference genome (panTro2) [ 18].

Shmulevich et al [ 48] constructed a probabilistic model of a small autonomous subnetwork of genes based on human glioma gene expression data [ 49] obtained for 588 known genes, in tissue samples with differing levels of glioma severity.

Gene annotation of somatic variants was done using custom script based on human mtDNA gene information (Ruiz-Pesini et al., 2007).

We propose deriving multiple factors, based on human cancer gene expression studies, from an experimentally defined signature.

An shRNA sequence (5′-GCAAGGCCAGTGGAGTTAATCCTCGAGGATTAACTCCACTGGCCTTGC-3′) was designed based on human lncRNA gene KIAA0125 (NR_026800).

Based on human RefSeq gene annotation from UCSC and 46 vertebrate species conservation (including primate and mammal subsets) (Table  1), we first show that blocks of highly conserved sequences are significantly enriched in first introns relative to other introns.

Therefore, mitochondrial function alteration and C3-implicated immune reaction/inflammation (complementary pathway activation is documented in Table 3) are likely to contribute at least partly to the hepatic steatosis in the current transgenic mice based on human NAFLD gene expression studies.