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Many prior studies of dementia have been based on highly selected clinical samples or community-based samples from geographically localized areas [ 3].
However, many of these prior studies have been based on highly selected clinical samples or community-based samples from geographically localized areas, thus raising questions about the generalizability of findings [ 3].
The published data were mostly based on highly selected clinical investigations or small studies.
These studies were based on highly selected samples, and our study is the first to report nationwide incidence.
Published data concerning salvage treatment is most often based on highly selected series of patients in whom intensive treatment is possible [ 4, 6, 10– 121 21– 25].
Fourth, the study results are based on highly selected patients using the propensity score methods, which limit the external validity [ 28] of the findings, despite confirmation of internal validity by conventional regression methods.
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Thus, the study results were based on a highly selected study cohort with a relatively small sample size and the risk of selection bias is high.
28 We note their technical superiority and that they are based on a highly selected population of healthy, optimally fed infants with relatively low statistical variance.
The study was performed in a nonrandomized, retrospective setting based on a highly selected patient population (only 13% of all treated patients had received three lines of targeted therapy).
Firstly, trials are conducted on highly selected populations [ 8].
This mainly depends on highly selected group of patient samples.
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