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CTCF may serve as the initial binding factor, defining a grid of potential insulation sites based on high specificity sequence motifs.
They are based on high specificity of phages to certain bacteria species, and their detection limit is 10 10 cfu/mL.
Our point is that in certain circumstances there may be a selective benefit to interpretive behaviour at one stage of evolution which is then superseded by a more efficient non-interpretive strategy based on high specificity binding.
The optimum cut-off value for the predicted probability of the model (i.e. the probability at which the model outcome correctly identifies an observed positive patient as positive) was chosen based on high specificity in order to minimize FN outcomes.
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The cutoff values we propose are based on higher specificity and higher positive likelihood ratio, as the purpose was to prevent further significant hyperbilirubinemia.
As well, based on higher specificity values associated with using VSI, fewer patients were exposed to unnecessary procedures (i.e., FP thus improving quality of care.
In contrast, this manuscript explores an alternative encapsulation strategy based on high-specificity avidity between a small molecule drug and its cognate protein target fused to the corona of protein polymer nanoparticles.
It is important to note that depending on the goals of diagnosing cows with CE or SCE one could use a different approach such as choosing a threshold based on high sensitivity or high specificity.
Cutoff values were chosen based on highest sensitivity and specificity to predict outcome using the roctab/detail function (Stata 11.0).
Based on highest sensitivity and specificity (ROC curve data not shown), posterior tilt was then dichotomized into < 20° or ≥ 20°.
The cut off value, based on higher sensitivity and specificity of L. infantum SLA, was established as 0.01685.
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