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We have identified a CSC population in ESFT cell lines and xenografts based on high expression of ALDH.
Based on high expression level and early plaque formation line ARTE10-729 waselecteded for propagation and subsequent analysis.
Comparing the gene expression profile of un-treated and treated melanoma cells implicated Wnt signaling based on high expression of the Wnt antagonist SFRP1 only in sensitive cells, which led us to further explore downstream members of this pathway and to identify activated β-catenin as a feature contributing to drug resistance.
The first 18 regions (Table 2) were chosen based on high expression levels of adjacent genes in placenta as ascertained from RNA-seq data (Jin et al. unpublished data).
Five miRNA candidates, miR-30c, miR-146a, miR-221, miR-328, and miR-375, were selected from the miRNA screen carried out using the discovery cohort based on high expression levels and high discriminatory capacity.
A clear role for TcBBM in the embryogenic process is none-the-less evident based on high expression throughout embryo development as well as in the embryogenic calli but not in the non-embryogenic calli.
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In a global ranking based on highest expression levels at day 6, the three predicted hydrophobins encoded by An03g02400, An08g09880 and An03g02360 were at positions one, five and six, respectively.
Clone selections were based on high luciferase expression in absence of doxycycline (Figure 1B).
Stem cell activity can be enriched by >200 fold (over 80% of activity), based on high Lrp5 expression alone.
It will be important to know whether high-risk patients for skeletal metastases can be identified based on high RANK expression in their primary breast tumours.
A third level was described recently, which is based on high XIAP expression, which prevents caspase activation and may be overcome by release of Smac.
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based on high volume
based on high growth
based on βgal expression
based on high intensity
based on high throughput
based on high gain
based on high school
based on high traffic
based on high visibility
based on high speed
based on high modulus
based on high level
based on mRNA expression
based on high quality
based on high temperature
based on high principle
based on high confidence
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