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Additionally, incremental and verification phase V̇O2 comparisons should be performed on an individual basis and not based on group means comparisons.
The recombinant inbred (RI) method exploits the fact that the individuals within each line are genetically identical, hence trait values are based on group means as opposed to individual measurements.
We normalized all data through conversion to z-scores based on group means.
Each graph also includes the normal distributions expected (based on group means and variances) if only random variations were involved.
As a result, we take an alternative approach by conducting test-retest analysis based on group means, along the lines suggested by Cooke and Szumal (1993) [ 23].
While the SRM statistic is closely related to the ability to detect statistically significant differences based on group means and between-patient variability, the RCP statistic relates in a similar way to the ability to detect treatment effects in individuals.
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Distress trajectories based on group mean values are problematic.
In contrast to the individual scores, the grades based on group mean scores between two time points showed substantial agreement estimated by weighted kappa values (p < 0.001).
The former are generally based on group mean data for symptoms, lung function and exacerbations, as well as safety, availability and overall cost.
For content quality, the grades based on group mean scores for all raters showed substantial agreement between two time points, however this was not the case for the grades based on individual rater scores.
The similarity in the pooled distribution of blood-Hg values between sampling events, based on group mean values that did not differ over time, is consistent with previous observation made by Tsuchiya et al. [ 7] in hair samples.
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