Sentence examples for based on global sequence from inspiring English sources

Our method was also compared to one based on global sequence similarity, using the BLAST alignment bitscores as illustrated in Materials and Methods.

Since the amino acids and the groups of amino acids in these sequence motifs represent critical positions conserved in evolution, search algorithms employing the EMOTIF patterns can identify and classify more widely divergent sequences than methods based on global sequence similarity.

Another null model, based on global sequence similarity, exploits the BLAST alignment bitscores.

It is thus difficult to speculate on the function of MmNQO based on global sequence comparison.

By partitioning sequences into clusters based on global sequence similarity, HHblits pre-computes discretized hidden Markov models (HMMs) on each cluster and only searches a query against those HMMs.

Specifically, the presence of gene pairs or gene clusters of closely homologous genes based on global sequence similarity with threshold of more than 60% amino acid sequence identity using cd-hit program of CD-HIT package were investigated.

Applying the FAST-NMR method on previously annotated systems also enables experimental ligand binding site data to identify functional relationships that otherwise would not be recognized based solely on global sequence and structure similarity.

Extracted sequences were reordered based on global similarity to the query sequence with MAFFT using the minimum linkage clustering method and rough distance measure (number of shared 6mers) (Katoh et al. 2005).

In most cases the trees are presented in unrooted radial form and are based on global alignments of protein sequences from one or two representative genera of each major taxon.

In the same way that global classification of the spaces of protein sequences and structures provided important biological information, studies of metabolism based on global classifications such as the one proposed here may also provide valuable data.

Whole genome or transcriptome sequencing enables functional genomic studies based on global gene expression.