Exact(10)
We based our pipeline on the popular novel transcript discovery programs, Cufflinks (Trapnell et al. 2012) and Trinity (Grabherr et al. 2011), with the former for genome-based transcript discovery and the latter for de novo assembly of transcripts not based on genomes.
targeted advertising or insurance premiums based on genomes.
We show that this solution quickly outcompetes strategies based on genomes with a high degree of neutrality.
3) Inefficient or time-consuming annotation - Annotating reads/contigs based on genomes of known species in the database may take a long time when certain errors are allowed during alignment.
This could be due to difficulties in predicting hydrophobic, membrane bound proteins, but also to the immaturity of proteome annotations, many of which are based on genomes recently released; but distinct functions in unexpected organelles should not be precluded.
Based on genomes of 137 prokaryotic isolates from global ocean surfaces, there was a preference for slow growth in most cosmopolitan lineages of dominant abundance, whereas minor species apparently switched between slow and fast growth under ambient conditions [ 14].
Similar(50)
The first one is based on genome-wide selection scans (GWSS) to detect outliers or structure violations as the signatures of selection.
The genetic mechanisms that underlie the individual variation have been investigated through approaches based on genome sequencing.
A genome-scale metabolic model, iJM658, was reconstructed based on genome annotation and literature mining.
We developed an unbiased integrative approach based on genome engineering, robust tracking methodology, and advanced analytics.
Complementary approaches based on genome sequence information and subsequent annotation of biosynthetic pathways are emerging technologies.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com